Zoe looks super cool. I remember this coming out a while ago as closed source, but the source code is now available. Unfortunately, it's under an Apple Public Source-style license which is not GPL compatable.

Come on people! Make your code compatable with the GPL!

I would also like to see its features in a richer client than the browser. I don't want to write mail (or anything else, for that matter) in a TEXTAREA. That's why I've got a mail client. Hopefully a rich-client will build upon Zoe's ideas. However, having this your personal data available from anywhere is sweet. I'm doing that with AmphetaDesk right now, and it rocks.